Greg is currently interested in how the physical nature of a cell’s interior is controlled and how aberrant signaling changes the physical properties of cells during cancer progression. These questions relate to how cells adapt to mechanical stresses.
Tamas Szoradi, Post Doc
Tamas was born and grew up in Budapest, Hungary. More precisely, on the right bank of the Danube in Buda. After finishing his BSc. and MSc. studies at the ELTE University in Budapest he moved to Heidelberg, Germany to pursue his PhD studies in the group of Sebastian Schuck at the Center for Molecular Biology (ZMBH). There he uncovered and characterized SHRED a novel stress response pathway in budding yeast.
In July 2018 he joined the lab as a post-doctoral fellow. He has started to investigate the biophysical properties of the nucleus with a particular emphasis on macromolecular crowding. He will use his expertise in molecular biology, biochemistry and yeast genetics (and maybe in guitar playing and climbing) to understand how crowding is mechanistically regulated.
Liam is interested in biological information processing, which can be thought about using the approaches of systems biology, quantitative cell biology, physics, cell biology, proteomics (and other omics) and science communication.
Alumni of the Holt lab
Here are some great members of the Holt lab from UC Berkeley and NYU
Morgan Delarue, Now a powerful Group Leader in Toulouse!
Morgan is from Rouen, the mighty capital of Normandy, France. He did his Ph. D. at the Curie Institute in Paris, and a first post doc at UC Berkeley (where he met Liam). He then came to do a post doc with us!
Morgan now has a PI position as a CNRS researcher in LAAS, Toulouse, France. His main research is focused on developing micro-devices to study how mechanical stresses and chemical signals couple to drive a specific phenotype. He studies some of these fundamental questions in yeast as a model system, and applies his findings to cancer. We will visit him frequently to collaborate on cassoulet. Don’t hesitate to contact him if you wish to know more! He’s recruiting, and he’s amazing. Check out his website here:
Noemie grew up in a small city in the South of Paris. She is interested in genetics since her 8th grade. After high school, she get a bachelor's degree in medicine at Paris Descartes University. She then chose to enter a research career. So, she is currently doing a master's degree of genetics at Paris Diderot University. During her time in Holt Lab, she worked in the effects of compressive stresses on the pathogen Candida albicans. She is interested in different (to many) subjects as evolutionary genetics, bioinformatics, genomics, microbiology and cell imaging."